Adenine nucleotide content of red blood cells of normal individuals and of patients suffering from Hodgkin's disease and other diseases.

LTFI()UGII TI-IE PRESENCE of adenninue mnmn(-leotides inn the blood was (hes(-nih)ed as eamly as 1914, a(lequate (hunamntitative studies wene riot made until 1935 when Bunell’ devised a nnepholometn-ic methol. Sine established the fact that tine nnun(-leoti(ies n -ere pmesennt cx(-lusively in the cellunlan componemnt, that the len-el for annv onne individual n as comnstamnt over a pem-iod of scvemal monnths, that the average valune fom males was about 1 1 .5 mg. per cent expressed as adenninne, and for females 10 mg. pen(emit. Subsequnenitly Albaum amid Lipshitz2 amid Albaum, Cavle anal Shnapim-o3 extenn(ied these oi)scnvationns I)y usinng a nnew quamitit-ative method based omi enzyme technnics oniginially (hescrihed I)y I alckam.46 These wonkems nnot only (-omnhnmecl Buell’s fimndinngs as to i)lood levels of total ademnimne